JPH0213647B2 - - Google Patents

Info

Publication number
JPH0213647B2
JPH0213647B2 JP57071494A JP7149482A JPH0213647B2 JP H0213647 B2 JPH0213647 B2 JP H0213647B2 JP 57071494 A JP57071494 A JP 57071494A JP 7149482 A JP7149482 A JP 7149482A JP H0213647 B2 JPH0213647 B2 JP H0213647B2
Authority
JP
Japan
Prior art keywords
hyperlipidemia
pronase
drugs
side effects
values
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57071494A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58189122A (ja
Inventor
Shigemi Fujisaki
Takashi Fujisaki
Junichi Yoshida
Takahiro Fujisaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAKEN SEIYAKU KK
Original Assignee
KAKEN SEIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KAKEN SEIYAKU KK filed Critical KAKEN SEIYAKU KK
Priority to JP57071494A priority Critical patent/JPS58189122A/ja
Priority to US06/484,313 priority patent/US4440749A/en
Priority to GB08310184A priority patent/GB2121685B/en
Priority to DE19833315482 priority patent/DE3315482A1/de
Priority to FR8307188A priority patent/FR2525901B1/fr
Publication of JPS58189122A publication Critical patent/JPS58189122A/ja
Publication of JPH0213647B2 publication Critical patent/JPH0213647B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/2404—Serralysin (3.4.24.40)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP57071494A 1982-04-30 1982-04-30 高脂血症予防治療剤 Granted JPS58189122A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP57071494A JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤
US06/484,313 US4440749A (en) 1982-04-30 1983-04-12 Preventive and treating agent for blood lipids abnormality and/or arteriosclerosis
GB08310184A GB2121685B (en) 1982-04-30 1983-04-14 Protease compositions for treating blood lipids abnormality and arteriosclerosis
DE19833315482 DE3315482A1 (de) 1982-04-30 1983-04-28 Mittel zur verhinderung und behandlung von blutlipid-abnormalitaet und/oder arteriosclerose
FR8307188A FR2525901B1 (fr) 1982-04-30 1983-04-29 Agent de prophylaxie et de traitement des anomalies des lipides sanguins et/ou de l'arteriosclerose, a base d'une enzyme proteolytique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57071494A JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤

Publications (2)

Publication Number Publication Date
JPS58189122A JPS58189122A (ja) 1983-11-04
JPH0213647B2 true JPH0213647B2 (en]) 1990-04-04

Family

ID=13462269

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57071494A Granted JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤

Country Status (5)

Country Link
US (1) US4440749A (en])
JP (1) JPS58189122A (en])
DE (1) DE3315482A1 (en])
FR (1) FR2525901B1 (en])
GB (1) GB2121685B (en])

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0676339B2 (ja) * 1985-09-13 1994-09-28 浩 前田 制癌剤
JP3054190B2 (ja) 1989-01-27 2000-06-19 イムノリティックス・インコーポレイテッド 良性前立腺肥大処置のための組成物および方法
US5116615A (en) * 1989-01-27 1992-05-26 Immunolytics, Inc. Method for treating benign prostatic hypertrophy
JPH02292226A (ja) * 1989-05-08 1990-12-03 Shigemi Fujisaki 障害された神経細胞賦活予防治療剤
NL9201842A (nl) * 1992-10-23 1994-05-16 Teng Hian Khoe Toepassing van een papaine bevattend voedingssupplement voor therapeutische behandeling van AIDS aandoeningen.
GB9403344D0 (en) * 1994-02-22 1994-04-13 Cortecs Ltd Medical application of bromelain
DE102005002255A1 (de) 2005-01-18 2006-07-20 Rehau Ag + Co. Wandanschlussprofil

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB753134A (en) * 1952-09-17 1956-07-18 Nat Drug Co An injectable trypsin containing pharmaceutical composition and method for its production
GB894151A (en) * 1958-01-29 1962-04-18 American Cyanamid Co Preparation of high purity streptokinase
US3224942A (en) * 1962-01-15 1965-12-21 Rorer Inc William H Anti-inflammatory, anti-edema and anti-thrombi drug
DE1249797B (de) * 1963-06-29 1967-09-14 Behringwerke Aktiengesellschaft, Marburg/Lahn Verfahren zur Herstellung von Streptokinase-Präparaten verminderter Antigenität
US3355361A (en) * 1964-10-15 1967-11-28 Sterling Drug Inc Recovery and purification of urokinase
GB1139991A (en) * 1965-07-19 1969-01-15 Armour Pharma Stabilized enzyme composition
GB1185335A (en) * 1967-05-30 1970-03-25 Takeda Chemical Industries Ltd A method for producing Protease
GB1263956A (en) * 1969-09-26 1972-02-16 Ici Ltd Enzymes
GB1274604A (en) * 1971-02-18 1972-05-17 Wilson Pharm & Chem Corp Pancreatin composition and method of preparation
GB1390541A (en) * 1971-04-14 1975-04-16 Otsuka Kagaku Yakuhin Anti-inflammatory compositions
JPS5443074B1 (en]) * 1971-04-14 1979-12-18
BE786788A (fr) * 1971-07-27 1973-01-26 Rhone Poulenc Sa Nouvelle enzyme thrombolytique et sa preparation par fermentation d'un streptomyces
JPS5039151B2 (en]) * 1972-09-02 1975-12-15
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
GB1448276A (en) * 1973-09-15 1976-09-02 Eisai Co Ltd Elastase and methods for using same
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
JPS5473107A (en) * 1977-11-24 1979-06-12 Keigo Takeda Germicide for special coccus *not disinfected one kind of antibiotics*
JPS5543040A (en) * 1978-09-25 1980-03-26 Eisai Co Ltd Immunity raising agent
IT1170913B (it) * 1981-04-23 1987-06-03 Manetti & Roberts Italo Brit Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche
JPS5826822U (ja) * 1981-08-17 1983-02-21 株式会社クボタ 刈取収穫機

Also Published As

Publication number Publication date
FR2525901A1 (fr) 1983-11-04
US4440749A (en) 1984-04-03
FR2525901B1 (fr) 1988-08-26
DE3315482C2 (en]) 1992-07-16
DE3315482A1 (de) 1984-01-12
GB8310184D0 (en) 1983-05-18
JPS58189122A (ja) 1983-11-04
GB2121685B (en) 1986-05-21
GB2121685A (en) 1984-01-04

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